Grenx

Objectives To investigate the association between green tea consumption and liver cancer incidence. Methods: We prospectively followed 41,761 Japanese adults aged 40–79 years, without a history of cancer at the baseline or any missing data for green tea consumption frequency. Cox proportional hazards models were used to calculate hazard ratios (HR) with 95% confidence intervals (CI), adjusted for age, alcohol drinking, smoking, the consumption of coffee, vegetables, dairy products, fruit, fish, and soybean. Results Over 9 years of follow-up, among 325,947 accrued person-years, the total incidence of liver cancer was 247 cases. We found that green tea consumption was inversely associated with the incidence of liver cancer. In men, the multivariate-adjusted HRs (95% CIs) for liver cancer incidence with different green tea consumption categories were 1.00 (reference) for\1 cup/day, 0.83 (0.53–1.30) for 1–2 cups/day, 1.11 (0.73–1.68) for 3–4 cups/day, and 0.63 (0.41–0.98) for C5 cups/day (p for trend = 0.11). The corresponding data among women were 1.00 (reference), 0.68 (0.35–1.31), 0.79 (0.44–1.44), 0.50 (0.27–0.90) (p for trend = 0.04). Conclusions Green tea consumption is associated with a reduced risk of liver cancer incidence.

“Following over 40,000 individuals for 9 years has shown a strong association between decreasing the risk of liver cancer and drinking green tea.  Liver cancer is the 6th most common cancer and drinking 5 or more cups of fresh green tea per day significantly decreases the risk of liver cancer.” – Josh Smith

Body Weight Loss and Weight Maintenance in Relation to Habitual Caffeine Intake and Green Tea Supplementation.  Obesity Research (2005) ;13:1195–1204. 

Objective: Investigation of the effect of a green tea-caffeine mixture on weight maintenance after body weight loss in moderately obese subjects in relation to habitual caffeine intake.

Research Methods and Procedures: A randomized placebo-controlled double blind parallel trial in 76 overweight and moderately obese subjects, (BMI, 27.5 ± 2.7 kg/m2) Matched for sex, age, BMI, height, body mass, and habitual caffeine intake was conducted. A very low energy diet intervention during 4 weeks was followed by 3 months of weight maintenance (WM); during the WM period, the subjects received a green tea-caffeine mixture (270 mg epigallocatechin gallate; 150 mg caffeine per day) or placebo.

Results: Subjects lost 5.9 ±1.8 (SD) kg (7.0 ± 2.1%) of body weight (p ≥ 0.001). At baseline, satiety was positively, and in women, leptin was inversely, related to subjects’ habitual caffeine consumption (p ≥ 0.01). High caffeine consumers reduced weight, fat mass, and waist circumference more than low caffeine consumers; resting energy expenditure was reduced less and respiratory quotient was reduced more during weight loss (p ≥ 0.01). In the low caffeine consumers, during WM, green tea still reduced body weight, waist, respiratory quotient and body fat, whereas resting energy expenditure was increased compared with a restoration of these variables with placebo (p 0.01). In the high caffeine consumers, no effects of the green tea-caffeine mixture were observed during WM.

Discussion: High caffeine intake was associated with weight loss through thermogenesis and fat oxidation and with suppressed leptin in women. In habitual low caffeine consumers, the green tea-caffeine mixture improved WM, partly through thermogenesis and fat oxidation.

“This was a great article to provide more understanding about the correct amount of green tea to consume to improve weight loss.  However, the greatest insight from this double-blind clinical trial was the difference green tea made in the weight maintenance phase versus high caffeine consumption.”  – Josh Smith